Selank
A synthetic anxiolytic/nootropic peptide derived from tuftsin.
Research peptideLimited
Identity
- Class
- Synthetic heptapeptide (tuftsin analog)
- Source
- Synthetic; based on the immunopeptide tuftsin
- Receptor
- No single established receptor; effects on GABA/serotonin and immune signaling proposed
Key properties
Molecular weight
≈ 751.9 Da
Approximate values for the native hormone. Engineered analogs are often deliberately larger and far longer-acting.
Mechanism
Selank is a synthetic heptapeptide based on the immune-active fragment tuftsin, developed (largely in Russia) as an anxiolytic and nootropic. Proposed effects touch GABAergic, serotonergic, and immune signaling, but well-controlled independent human evidence is limited.
Reference notes
- Derived from tuftsin, an endogenous immunomodulatory peptide fragment.
- Developed primarily outside large international trial programs; independent evidence is limited.
- Mechanism is proposed across several systems rather than firmly established.
Selected literature
Curated peer-reviewed reviews, sourced from PubMed. Selected for relevance, not exhaustive — open any entry on PubMed for the full record and its primary citations.
- 1.Tuftsin - Properties and Analogs · Current medicinal chemistry, 2017 · PMID 28745220